AB0251 * FATIGUE IN RHEUMATOID ARTHRITIS: DOES PATIENT AGE INFLUENCE?

Background Fatigue in RA has a multi-causal pathway. It is recommended that it should be measured all studies using validated instrument. elderly patients could have different perception than younger patients, identifying the associated factors key to management of this complex symptom. Objectives To compare fatigue and its young with from two university hospitals. Methods A cross-sectional analysis was performed 167 diagnosed according 2010 ACR-EULAR criteria. Patients were divided into groups based on age (≥60 <60) for comparative purposes. assessed 4 instruments: Bristol Rheumatoid Arthritis Multidimensional Questionnaire (BRAF-MDQ), subscale Short-form 36 survey (fatigue-SF36), Visual Analogic scale (VASf) Functional Assessment chronic illness Therapy Scale (FACIT-F). mean between we used T-Test. determine each group (young patients) relationship subscales (assessed by BRAF-MDQ) other variables (DAS28, CPR, ESR, hemoglobin, vitamin D, HAQ, RAID [Rheumatoid Impact Disease], SF36, Hospital Anxiety depression [HAD] Brief Pain Inventory) Spearman correlation performed. value p < 0.05 accepted as statistically significant. Results total included, 81 (48.5%) 86 (51.5%) patients. We found (using instruments) not significant differences (Table 1). In physical, living, cognitive emotional correlated RAID, HAD pain but they CRP, hemoglobin D. dimensions DAS28. Furthermore, physical (p-value 0.044) living 0.012) DAS28, nevertheless 0.078 0.079 respectively) related. Table 1. Scores Questionnaires assess RA. Young Mean (SD) Elderly p-value FACIT-F 36.5 (12.5) 35.9 (11.7) 0.2963 VAS-F 4.3 (2.8) 3.8 0.119 SF36-Fatigue 50.9 (23.9) 51.0 (21.9) 0.628 BRAF-MDQ Physical 9.2 (6.2) 8.5 (6.3) 0.4670 Living 5.3 (5.6) 4.2 (4.6) 0.1446 Cognitive 3.3 (3.8) 0.2932 Emotional 3.5 (3.5) 2.6 (2.7) 0.0932 Conclusion appear related subjective objective variables. DAS28 only correlate disease activity. These results indicate important evaluate multidimensional perspective References [1]Belza BL, Henke CJ, Yelin EH, Epstein WV, Gilliss CL. Correlates older adults rheumatoid arthritis. Nurs Res. 1993 Mar-Apr;42(2):93-9. [2]Hewlett S, Dures E, Almeida C. Measures fatigue: MultiDimensional (BRAF MDQ), Numerical Rating Scales NRS) severity, effect, coping, Chalder (CFQ), Checklist Individual Strength (CIS20R CIS8R), Severity (FSS), Chronic Illness (Fatigue) (FACIT-F), Multi-Dimensional (MAF), Inventory (MFI), Pediatric Quality Of Life (PedsQL) Scale, Profile (ProF), Short Form Vitality Subscale (SF36 VT), Analog (VAS). Care Res (Hoboken). 2011 Nov;63 Suppl 11:S263-86. Disclosure Interests None declared